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Quantitative determination of vitamins A, E, and coenzyme Q10 in DBS by LC-MS/MS technique

  • Test objective: Detection of deficiencies or excesses of vitamins A and E and coenzyme Q10, helpful in diagnosis:
    • visual disturbances, skin lesions, immune disorders (vitamin A)
    • habitual miscarriages, anaemia, muscular dystrophies (vitamin E)
    • impaired cell metabolism and antioxidant capacity (coenzyme Q10)
  • Method of testing: High performance liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS)
  • Analysed substances: Retinol (vitamin A), Tocopherol (vitamin E), Ubiquinone (coenzyme Q10)
  • Type of test material: Dried blood spot
  • Test category: DBS