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Quantitative determination of vitamins A, E, and coenzyme Q10 in DBS by LC-MS/MS technique

  • Test objective: Detection of deficiencies or excesses of vitamins A and E and coenzyme Q10, helpful in diagnosis:
    • visual disturbances, skin lesions, immune disorders (vitamin A)
    • habitual miscarriages, anaemia, muscular dystrophies (vitamin E)
    • impaired cell metabolism and antioxidant capacity (coenzyme Q10)
  • Method of testing: High performance liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS)
  • Analysed substances: Retinol (vitamin A), Tocopherol (vitamin E), Ubiquinone (coenzyme Q10)
  • Type of test material: Dried blood spot
  • Test category: DBS

Vitamins A, E and Coenzyme Q10 testing from dried blood spot — patient-centric sampling

Masdiag Laboratory offers vitamins A, E and coenzyme Q10 analysis from dried blood spot (DBS) using validated LC-MS/MS methodology. DBS is a patient-centric sampling approach — the patient collects a few drops of capillary blood at home with a simple finger prick, dries the sample on filter paper, and ships it to our laboratory via standard post. No clinic visit. No cold chain. No venipuncture.

This approach is increasingly adopted by supplement companies, nutraceutical brands, health tech platforms and clinical research organisations as a scalable, convenient alternative to conventional blood testing.

Test material: Dried blood spot (DBS), serum, plasma  |  Method: LC-MS/MS  |  ISO 15189 compliant  |  Available for: individual patients · supplement brands · nutraceutical efficacy studies · international partners