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Quantitative determination of glutathione index in DBS by LC-MS/MS technique

  • Test objective: Determination of glutathione index (GSH/GSSG ratio) is performed to assess the redox state ofthe cell and the body's ability to counteract oxidative stress.
  • Method of testing: High-performance liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS
  • Analysed substances: Glutathione (GSH), Glutathione disulfide (GSSG).
  • Type of test material: Dry blood spot, Whole blood drawn on EDTA
  • Test category: DBS, Metabolomics

Glutathione index (GSH/GSSG) testing from dried blood spot — patient-centric sampling

Masdiag Laboratory offers glutathione index (GSH/GSSG ratio) analysis from dried blood spot (DBS) using validated LC-MS/MS methodology. DBS is a patient-centric sampling approach — the patient collects a few drops of capillary blood at home with a simple finger prick, dries the sample on filter paper, and ships it to our laboratory via standard post. No clinic visit. No cold chain. No venipuncture.

This approach is increasingly adopted by supplement companies, nutraceutical brands, health tech platforms and clinical research organisations as a scalable, convenient alternative to conventional blood testing.

Test material: Dried blood spot (DBS), serum, plasma  |  Method: LC-MS/MS  |  ISO 15189 compliant  |  Available for: individual patients · functional medicine programmes · supplement efficacy studies · international partners