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Quantitative determination of homocysteine in DBS by LC-MS/MS technique

  • Test objective: Homocysteine determination is performed, among other things, as part of the diagnosis of cardiovascular diseases, as well as in the case of suspected vitamin B12 and folic acid deficiency.
  • Method of testing: High-performance liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS).
  • Analysed substance: Homocysteine (Hcy)
  • Type of test material: Dried blood spot, serum, plasma
  • Test category: DBS, Metabolomics

Homocysteine testing from dried blood spot — patient-centric sampling

Masdiag Laboratory offers homocysteine analysis from dried blood spot (DBS) using validated LC-MS/MS methodology. DBS is a patient-centric sampling approach — the patient collects a few drops of capillary blood at home with a simple finger prick, dries the sample on filter paper, and ships it to our laboratory via standard post. No clinic visit. No cold chain. No venipuncture.

This approach is increasingly adopted by supplement companies, nutraceutical brands, health tech platforms and clinical research organisations as a scalable, convenient alternative to conventional blood testing.

Test material: Dried blood spot (DBS), serum, plasma  |  Method: LC-MS/MS  |  ISO 15189 compliant  |  Available for: individual patients · cardiovascular health programmes · supplement efficacy studies · international partners