Quantitative determination of the fatty acid profile in DBS by GC-FID
- Test objective: Analysis of the fatty acid profile is an important element in the prevention and treatment of cardiovascular diseases, neurological disorders and diet-related diseases. The results of the study enable individual adjustment of the diet and/or supplementation, and thanks to the use of indicators (Omega-3 Index, Trans Fat Index, Omega-6: Omega-3 ratio, AA: EPA ratio) they show mutual proportions of fatty acids.
- Method of testing: Gas Chromatography (GC) with Flame Ionization Detection (FID)
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Analysed substances:
- Omega-3 fatty acids: alfa-linolenic acid (ALA, 18:3n3), eicosapentaenoic acid (EPA, 20:5n3), docosapentaenoic acid-n3 (22:5n3), docosahexaenoic acid (DHA, 22:6n3)
- Omega-6 fatty acids: linoleic acid (18:2n6), gamma-linolenic acid (18:3n6), eicosadienoic acid (20:2n6), dihomo-gamma-linolenic acid (20:3n6), arachidonic acid (AA, 20:4n6 ), docosatetraenoic acid (22:4n6), docosapentaenoic acid-n6 (22:5n6)
- Cis-monounsaturated fatty acids: palmitoleic acid (16:1n7), oleic acid (18:1n9), eicosenoic acid (20:1n9), nervonic acid (24:1n9)
- Saturated fatty acids: myristic acid (14:0), palmitic acid (16:0), stearic acid (18:0), arachidic acid (20:0), bohenic acid (22:0), lignoceric acid (24:0 0)
- Trans fatty acids: trans-palmitooleic acid (16:1n7t), trans-oleic acid (18:1t), trans-linoleic acid (18:2n6t)
- Indicators: Omega-3 Index, Trans Fat Index, Omega-6 : Omega-3 Ratio and AA : EPA
- Type of test material: Dried blood spot
- Test category: DBS
Long-chain fatty acid profile testing from dried blood spot — patient-centric sampling
Masdiag Laboratory offers long-chain fatty acid profile (23 fatty acids including omega-3 and omega-6) analysis from dried blood spot (DBS) using validated LC-MS/MS methodology. DBS is a patient-centric sampling approach — the patient collects a few drops of capillary blood at home with a simple finger prick, dries the sample on filter paper, and ships it to our laboratory via standard post. No clinic visit. No cold chain. No venipuncture.
This approach is increasingly adopted by supplement companies, nutraceutical brands, health tech platforms and clinical research organisations as a scalable, convenient alternative to conventional blood testing.
Test material: Dried blood spot (DBS), serum, plasma | Method: LC-MS/MS | ISO 15189 compliant | Available for: individual patients · nutraceutical brands · supplement efficacy studies · international partners