Qualitative determination of SAICAR in urine by LC-MS/MS technique

Test objective: To diagnose adenylyl succinate lyase (ADSL) deficiency and AICAR transformase and IMP cyclohydrolase (ATIC) deficiency.
Method of testing: High-performance liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS).
Analysed substances: succinylaminoimidazolecarboxamide riboside (SAICAR) and succinyladenosine (S-Ado)
Type of test material: Urine (single urine sample)
Test category: Metabolomics